Yes, you run behind a line. However, there doesn't seem to be a mindset or scheme to run effectively. Lewis seems stuck on the idea wins will come behind Sanders and the wide receivers. At least the tight end was added and became effective.

They need to run the ball a lot more. Defenses can eventually stop a passing attack or make it struggle if that's the only thing an offense is doing. Dylan Edwards is a fine football player and no one will catch him when he gets in the open. The trouble comes when they try to run a 170 pound back between the tackles without sufficient blocking at the point of attack. He is stopped cold when he contacts linemen who are 100 pounds heavier and linebackers who are 50-60 pounds heavier and plenty stronger than he is. They seem to be hoping there will be a giant hole he can accelerate through and say goodbye. It won't happen without a blocking scheme with sufficient blockers in front of him at the point of attack. Furthermore, a bigger stronger back can attack a lineman or linebacker when he is contacted and has a chance to break the tackle for additional yards.

Their running game is a complete waste of time without a blocking scheme and intention to do it successfully other than a random attempt here or there with no scheme. The touchdown run by Wilkerson against TCU occurred with a mindset and scheme to do it. The big backs need to be used with purpose. There are ways to get Edwards outside or off tackle where he has room to accelerate and leave people behind. Anyone who knows a little bit about football knows what I have in mind without me going much further into the discussion. (Swing pass, pitch out. Pulling lineman or blocking back out in front for off tackle, sweep or swing pass.)